
One guy acting strangely is a nut. A bunch of people doing the same thing is called a church. - Shawn Mahaney
A high-tech process
This might surprise you, in an age full of high-tech 3D modelling software, but for many companies, the next
stage is a fantastically nostalgic regression to methods seemingly more suited to the 1900s - a pencil, paper and a
pair of scissors!
Yes, trying to work out where the main components should go is perhaps a thousand times easier to do by pushing life-sized cut-outs of the chips and bits around on a drawing of your target PCB, say for example, an ATX board, complete with all the possible mounting holes and where the slots should go, than it would be in CAD.
What we want
There are a few things that you're trying to achieve here:
For example, on a north bridge, you would hope that the designer would put the CPU interface at the top right, the memory interface at the bottom right, the PCI express graphics at the top left, and the south bridge connection at the bottom left.
Let's look at the Intel P965 layout below to see how this works in real life!

And, as you'd hope, everything matches a typical ATX board nicely - so draw Pin A1 and the main interfaces on your piece of paper, and you know roughly where and in which direction to point the chip.
Get it wrong, and what happens is pretty nasty - you will end up with signals criss-crossing each other. Whenever that happens, you have to move from one electrical layer to the other, through something called a via - no relation to the chip company. These joints have both resistance and inductance, so delay high-speed signals. On a parallel bus, even if your stability remains OK, it still means that bit 1 may arrive after bit 4, and it restricts how fast you can clock it - overclocker's nightmare!
If you have lots of signals that need to change layers, you're also likely to need more layers overall. PCBs typically come in 2, 4, 6 or 8 layers, with a usually motherboard taking four (two signals, one power and one ground plane). Go from four to eight layers, just because you have placed things badly, and you'll nearly quadruple the cost of the PCB. Ouch!
Getting it all together
So when you've got the bits of paper all right, and are happy about how things will be routed, generally you'll
use a CAD program to create a DXF file with the overall dimensions and all the major bits on. This gets combined with
the netlist, the symbols and the bill of materials and dragged into your PCB design software so the nasty business of
routing can begin. µ